Electrospining Machine: Stimulus-Responsive Electrospun Nanofbers for Drug Delivery, Cancer Therapy, Wound Dressings, and Tissue Engineering

Background

Recently, Prof. Guoxin Tan et al. published a review summarizing the research progress of stimuli-responsive electrospun nanofibers as a smart drug delivery platform in biomedical field. The related research results were published under the title “Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering The research results were published in the Journal of Nanobiotechnology under the title “Stimuli-responsive electrospun nanofibers for drug delivery, cancer therapy, wound dressing, and tissue engineering”.

The main points of this paper

1.The preparation of stimulus-responsive Electrospun Nanofbers is reviewed.

2.The design strategies of various types of stimulus-responsive Electrospun Nanofbers are discussed.

3.The research progress of stimuli-responsive Electrospun Nanofbers in drug delivery, tumor therapy, wound dressing and tissue regeneration is presented.

4.The challenges and future development of stimuli-responsive Electrospun Nanofbers in clinical applications are presented.

(a) Schematic diagram of conventional electrostatic spinning equipment. (b) Schematic diagram of three commonly used methods for the preparation of stimulus-responsive electrospun nanofibers.

(a) Schematic synthesis of photothermal chemotherapeutic nano-agent ZCPC. (b) Electrostatic spinning arrangement of PCL/ schematic gel/ ZCPC fibers. (c) Schematic diagram of the healing mechanism of SD rat whole wound infection model.

Programmatic description of (a) the construction of a bio-inspired composite scaffold for the treatment of spinal cord injury and (b) its microenvironmental responsive immunomodulatory and neuroregenerative effects

Originallink: https://doi.org/10.1186/s12951-023-01987-z