Electrospining Machine:Want to get a quick overview of the progress of Electrospun Nanofbers in the field of tissue engineering?

Background

Electrospun Nanofbers have a wide range of applications in the field of tissue engineering due to their high specific surface area, biocompatibility, degradability, and multifunctionality. This content selects relevant literature to help you quickly understand the progress of Electrospun Nanofbers in the field of tissue engineering.

Recent Advances in Three-Dimensional Electrospun Nanofbers Scaffolds for Tissue Engineering

The variation of 3D tissue engineering scaffold structure, function and application depends on the choice of electrospinnig machine preparation method and the post-processing of Electrospun Nanofbers scaffolds. In this paper, the latest research progress of electrospun 3D Electrospun Nanofbers scaffold materials, as well as multiple 3D Electrospun Nanofbers scaffold preparation methods are reviewed and their advantages and disadvantages are compared. Finally, the current challenges and prospects of 3D Electrospun Nanofbers scaffolds are discussed, providing new ideas for their application in biomedical fields.

Highly elastic strain sensing maize protein Electrospun Nanofbers for monitoring wound healing

In this study, highly elastic corn protein ultrafine Electrospun Nanofbers scaffolds with a three-layer structure were designed for motion tracking in the unpacked state. A tightly crosslinked protein network was effectively established by introducing a highly reactive epoxy resin, and provided the fiber substrate with a wide range of stretchability (360% stretch range) and ultra-high elasticity (99.91% recovery) in the wet state. With the help of a polydopamine bonding layer, a silver conductive sensing layer was constructed on the protein fibers, giving the scaffold a wide range of strain sensing (264%), high sensitivity (measurement factor up to 210.55), short response time (<70 ms), reliable cycling stability, and long-lasting service life (up to 30 days). The unpackaged smart scaffold not only supports cell growth and accelerates wound healing, but also tracks movement within the skin and the body, triggering an alarm in the event of excessive wound deformation.

Electrospun Nanofbers Control Drug Delivery for Tissue Regeneration and Cancer Therapy

This study first describes the construction and various structures of Electrospun Nanofbers scaffolds, as well as various commonly used drug types. We then discuss some representative strategies for controlling drug delivery by Electrospun Nanofbers, with special emphasis on the design of endogenous and exogenous stimulus-responsive drug delivery systems. Subsequently, recent advances in Electrospun Nanofbers scaffolds for controlled drug delivery in tissue engineering, including soft tissue engineering (e.g., skin, nerve, and cardiac repair) and hard tissue engineering (e.g., bone, cartilage, and musculoskeletal systems), as well as in cancer therapy, are summarized. In addition, future directions and challenges for Electrospun Nanofbers for controlled drug delivery are presented, aiming to provide insights and perspectives for the development of smart drug delivery platforms to improve clinical therapeutic efficacy in tissue regeneration and cancer therapy.

Originallink:

https://doi.org/10.1007/s42765-022-00170-7,

https://doi.org/10.1021/acsnano.3c03087

https://doi.org/10.1007/s42765-022-00198-9