Electrospinning Equipment: Silk fibroin as a sustainable advanced material: material properties and characteristics, processing, and applications

Unique properties and application prospects of silk fibroin

Silk fibroin (SF) is a natural protein extracted from silkworm cocoons, which has excellent biocompatibility, biodegradability, low immunogenicity, adjustable mechanical properties and good water solubility. These properties make silk fibroin an ideal material for skin tissue engineering and wound healing. Silk fibroin can mimic the structure and function of the extracellular matrix and promote cell attachment, proliferation and differentiation.

Application of electrospinning equipment in silk fibroin materials

Electrospinning equipment can produce high-performance nanofibers with high specific surface area, high porosity and good biocompatibility, which are widely used in tissue engineering, drug delivery and other fields. Combining electrospinning technology with the research of silk fibroin can further improve the performance and application effect of the material:

Preparation of nanofiber structure: Electrospinning can produce uniform continuous fibers with diameters ranging from nanometers to micrometers. These fibers can be used to construct reinforced structures of silk fibroin-based materials and improve their mechanical properties and stability.

Regulating fiber morphology and arrangement: By adjusting the parameters in the electrospinning process (such as spinning solution concentration, viscosity, electric field strength, etc.), the diameter and morphology of the fiber can be precisely controlled, thereby optimizing the performance of the material.

Loading bioactive substances: Electrospinning equipment can prepare nanofiber scaffolds loaded with bioactive molecules, and by controlling the release rate, the sustained effect of bioactive substances in the skin tissue engineering site can be achieved.

Summary and Outlook

As a multifunctional natural material, silk fibroin can be processed through electrospinning technology to prepare nanofibers with excellent structure and performance, expanding its application in skin tissue engineering and wound healing. Future research can further explore the combination of electrospinning technology with other emerging technologies, such as nanotechnology, smart materials, etc., to achieve more complex and sophisticated structural design and functional regulation. In addition, the electrospinning process parameters and material selection can be optimized to improve the biocompatibility, mechanical properties and functionality of nanofibers, and promote the industrialization of silk fibroin-based materials.

Electrospinning Nanofibers Article Source:

https://doi.org/10.1002/adfm.202210764