Electrospinning Device: Biocompatible fluorescent silk bioink for digital light processing 3D printing

Background

Chemically modified silk biochains, such as fluorescent silk (FSE), have broad application prospects in the biomedical field due to their fluorescent properties. These biochains can be made into digital light processing (DLP) printable bioinks through covalent coupling, which are used for 3D printing of various complex biological structures, such as brains, ears, hands, lungs, etc.

Working principle of electrospinning equipment

Based on the action of electrostatic field, electrospinning equipment forms Taylor cones through polymer solutions or melts under strong electric fields, and then ejects fibers. This technology can produce nanoscale fibers, which are widely used in filtration materials, biomedicine, protective clothing and energy fields.

Combination of chemically modified silk and electrospinning equipment

Electrospinning technology can be used to prepare nanofibers of chemically modified silk protein. These nanofibers have important applications in tissue engineering and drug delivery systems due to their high specific surface area and biocompatibility. Through electrospinning equipment, chemically modified silk protein solutions can be made into nanofibers with specific structures and functions for use in the biomedical field.

Technological development and market situation of electrospinning equipment

The electrospinning equipment industry continues to grow globally, and the Chinese market occupies an important share. Technological innovation, material diversification, intelligence and automation are the keywords for the development of electrospinning equipment. At the same time, environmentally friendly electrospinning equipment will become the mainstream trend of the market.

Biocompatibility and fluorescence properties of chemically modified silk biochains

Chemically modified silk biochains, such as FSGMA hydrogels, retain fluorescence properties and have good biocompatibility, making them a powerful tool for cell tracking and observing the degradation of scaffolds in vivo.

Application prospects of electrospinning equipment in the biomedical field

Nanofibers prepared by electrospinning equipment have a wide range of applications in the biomedical field, including tissue engineering scaffolds, drug sustained release systems, and biosensors. The introduction of chemically modified silk protein can further expand these applications through electrospinning technology, especially in 3D bioprinting and cell tracking.

Summary

In summary, the combination of chemically modified silk biochains and electrospinning equipment provides new materials and methods for the biomedical field, especially in 3D bioprinting and cell tracking. The development and application of electrospinning technology will further promote the application of chemically modified silk fibroin in the biomedical field

Electrospinning Nanofibers Article Source:

https://doi.org/10.1016/j.ijbiomac.2022.05.123