Electrospinning Device: Development of quercetin-loaded silk fibroin/soy protein isolate hydrogel for burn wound healing

Views: 901 Author: Nanofiberlabs Publish Time: 2025-01-02 Origin: wound healing

Background

 

SF/SPI-Q hydrogel has good biocompatibility, biodegradability, antibacterial properties, antioxidant capacity and the ability to promote cell migration. These properties make it an effective means of burn wound repair. Electrospinning technology can prepare micro/nano fibers, which show great potential in tissue engineering and regenerative medicine due to their high specific surface area and porous structure. Combining the properties of SF/SPI-Q hydrogel and electrospinning technology, new biomedical materials can be developed for wound dressings, drug sustained release systems, etc.

 

Application of electrospinning technology in biomedical fields

 

Electrospinning technology has been used to manufacture fiber hydrogels as 2D/3D cell culture platforms, implantable scaffolds and wound dressings. This shows that electrospinning technology can be combined with hydrogels to produce structures with specific biomedical application value. The combination of the bioactivity of SF/SPI-Q hydrogel and the structural properties of electrospun fibers may provide new solutions in the biomedical field.

 

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Application of electrospinning technology in wound healing

 

Electrospinning technology can be used to prepare nanofibrous membranes with properties that promote wound healing. For example, by spinning functional polymers directly onto the site of skin damage to form a restorative nanofiber membrane, it is possible to promote the growth of normal skin and accelerate wound healing without the scars that are seen in traditional treatments. The addition of SF/SPI-Q hydrogels may enhance the performance of such nanofiber membranes and provide better antibacterial and antioxidant protection.

 

Electrospinning technology combined with hydrogels to manufacture 3D structures

 

Through the hydrogel-assisted electrospinning process (GelES), 3D nanofiber macrostructures with complex but tailored configurations can be manufactured. This technology can broaden the potential application range of electrospinning and provide freedom by increasing the configuration of 3D nanofiber macrostructures. The addition of SF/SPI-Q hydrogels may make these 3D structures more biocompatible and bioactive, suitable for in vivo drug/cell delivery and tissue regeneration.

 

Application of electrospinning technology in the food field

 

Electrospinning technology has also been applied in the food field, such as active substance embedding, food testing, new food development, food additives, etc. Although this is not directly related to SF/SPI-Q hydrogels, it demonstrates the versatility and cross-field application potential of electrospinning technology.

 

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Summary

 

In summary, the combination of SF/SPI-Q hydrogels and electrospinning technology has great application potential in the biomedical field, especially in wound healing and tissue engineering. Through electrospinning technology, nanofibers with specific structures and functions can be prepared, which combined with the biological activity of SF/SPI-Q hydrogels may develop new biomedical materials and treatments.

 


Electrospinning Nanofibers Article Source:

https://doi.org/10.1016/j.cej.2023.148458

 


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