Electrospinning Device: Functionalized nanoparticle/silk fibroin coating with anti-adhesion and photothermal properties for preventing implant-associated infection

Background

Electrospinning is an effective method for preparing nanofibers, which have a wide range of applications in the biomedical field due to their high specific surface area and porosity. In FNP/SF-Ti antibacterial coatings, silk fibroin (SF)-based nanofibers can be prepared by electrospinning technology, which can enhance the mechanical properties and biocompatibility of the coating.

Application of biomedical materials

The application of electrospun nanofibers in tissue engineering scaffolds, wound dressings, controlled drug release, etc. is similar to the application of FNP/SF-Ti antibacterial coatings. FNP/SF-Ti coatings use the biocompatibility and osteogenic properties of silk fibroin, which echoes the application of electrospinning technology in biomedical materials.

Antibacterial and anti-adhesion properties

Electrospinning technology can prepare nanofibers with antibacterial properties, such as by doping antibacterial agents in nanofibers or using the physical properties of nanofibers to inhibit bacterial adhesion. FNP/SF-Ti coating achieves dual functions of antibacterial and anti-adhesion by combining iron oxide nanoparticles (FNP) functionalized with polydopamine and polyethylene glycol with silk fibroin (SF).

Photothermal properties

Electrospinning technology can prepare nanofibers with photothermal properties, which can generate heat under light for photothermal therapy. FNP/SF-Ti coating uses the photothermal properties of iron oxide nanoparticles to kill attached bacteria under near-infrared light irradiation, which is similar to the application of electrospinning technology in the preparation of photothermal nanofibers.

Surface modification

Electrospinning technology can be used to improve the biocompatibility and functionality of material surfaces, such as by depositing nanofibers with specific functions on the surface to enhance the performance of the material. FNP/SF-Ti coating improves the antibacterial and biocompatibility of the surface by depositing FNP and SF on the titanium-based surface, which is consistent with the application of electrospinning technology in surface modification.

Summary

In summary, the connection between electrospinning technology and FNP/SF-Ti antibacterial coating is that they both use the unique properties of nanofibers to enhance the performance of materials, especially in biomedical, antibacterial, anti-adhesion and photothermal therapy applications. The application of these technologies provides new possibilities for the development of new biomaterials and the improvement of existing materials.

Electrospinning Nanofibers Article Source:

https://doi.org/10.1016/j.cej.2024.150147