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Electrospinning technology can produce fiber materials with high specific surface area and porous structure. These materials not only have good mechanical strength, but also have a three-dimensional structure similar to the extracellular matrix (ECM), which can provide the necessary support and guidance for cells, which is conducive to cell proliferation and the growth of new tissues.
Electrospinning materials can quickly and effectively stop bleeding due to their high specific surface area, while maintaining moisture in the wound, having strong air permeability and preventing the penetration of external microorganisms.
Electrospinning is an important technology for manufacturing micro/nano fiber platforms, which can be used for biomedical scaffolds for tissue engineering repair and regeneration. These scaffolds are widely used in drug/cell/growth factor release, antibacterial and anti-inflammatory, hemostasis, wound healing, tissue repair and regeneration.
Electrospinning nanofibers show extraordinary versatility, opening up countless possibilities in materials science, biomedicine and other fields. They can be integrated with other technologies such as microfluidic chips, microneedles, and electrostatic flocking for a variety of biomedical applications such as infection control, hemostasis, tissue regeneration, and biospecimen collection.
Hemostatic hydrogels help control bleeding and keep the wound site moist, which helps wound healing. Electrospinning technology can be used to form nanofiber matrices that control bleeding through their ability to capture blood cells, platelets, and other coagulation factors and their structural similarity to natural fibrin fibers.
Electrospinning technology is a common method for preparing nanofiber scaffolds for tissue engineering. For example, by preparing composite nanofibers made of cellulose acetate butyrate and hydrophilic polyethylene glycol, the performance of nanofibers is improved, with better cell attachment, which can be used as nanofiber scaffolds in tissue engineering.
In summary, the application of electrospinning technology in hemostatic hydrogels and wound dressings has significant advantages, including promoting wound healing, hemostasis, protecting wounds from infection, and serving as a drug release platform. These properties make electrospun materials a promising candidate in the medical field, especially in emergency wound management and tissue engineering.
Electrospinning Nanofibers Article Source:
https://pubs.acs.org/doi/10.1021/acsami.4c01686
