Electrospinning Device: Reinforced silk fabric for artificial bones

Background

Nanofibers prepared by electrospinning technology can provide excellent biocompatibility due to their high specific surface area and porous structure, which is conducive to cell adhesion and growth. As a new type of artificial bone material, SFS also shows excellent biocompatibility, which can promote the proliferation of osteoblasts and increase osteogenic activity.

Biodegradability

Electrospinning technology can prepare biodegradable nanofibers, which is particularly important in the fields of tissue engineering and regenerative medicine. SFS materials also have good biodegradability and can be gradually degraded in the body without secondary surgical resection, reducing patients' secondary pain and medical expenses.

Customization of mechanical properties

Electrospinning technology can control the mechanical properties of nanofibers, such as strength and toughness, by adjusting process parameters. The mechanical properties, biodegradation rate and density of SFS materials can also be customized by adjusting the reinforcement structure and the ratio of reinforcement to matrix to meet the requirements of bone implantation in different parts of the human body.

Preparation process of materials

Electrospinning technology involves forming fibers from polymer solutions through high-voltage electric fields, while SFS materials are made by fusing degummed silk fabrics with regenerated silk fibroin through hot pressing technology to form composite materials with high strength and customized properties.

Application prospects of materials

Nanofibers prepared by electrospinning technology have broad application prospects in the fields of medicine, environmental protection, energy, etc. As a new type of artificial bone, SFS material is expected to replace traditional metal or ceramic implants and has great application potential in the field of medical fracture repair.

Multifunctionality of materials

Electrospinning technology can prepare nanofibers with multiple functions, such as antibacterial and drug release. SFS materials not only have excellent mechanical properties and biocompatibility, but also can improve the proliferation of osteoblasts and increase osteogenic activity, which is not available in titanium alloy artificial bones used clinically.

Conclusion

In summary, electrospinning technology and SFS artificial bones are closely related in terms of biocompatibility, biodegradability, customization of mechanical properties, material preparation process, application prospects and multifunctionality. These connections suggest that electrospinning technology has important application potential in the development of novel biomedical materials and therapeutic strategies.

Electrospinning Nanofibers Article Source:

https://doi.org/10.1002/adma.202308748