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Electrospinning technology has shown great application potential in the field of dentistry, especially in the construction of periodontal regeneration materials, because it can prepare fiber materials with high specific surface area and porous structure. For example, Yang et al. used gelatin to combine multilayer electrospun polycaprolactone oriented nanofiber membranes to design a biological scaffold that simulates the structure of the periodontal complex, which can provide a good attachment surface for human periodontal ligament cells and simulate the tissue microenvironment, adapt to the directional growth of periodontal ligament fibers, and enhance the regeneration effect of periodontal tissue.
The silk protein-based lithium soapstone composite scaffold material developed by Tao Jiang's research group has good hemostatic and osteogenesis functions and excellent shape memory properties, which is consistent with the material properties prepared by electrospinning technology. Electrospinning technology can prepare nanofiber scaffolds with specific structures and functions, which can be used for efficient tooth extraction site filling.
Electrospinning technology is a common method for preparing nanofiber scaffolds for tissue engineering. For example, Hui-Li et al. prepared composite nanofibers made of cellulose acetate butyrate and hydrophilic polyethylene glycol, improved the performance of nanofibers, had better cell adhesion, and could be used as nanofiber scaffolds in tissue engineering.
Electrospinning fibers also have good application prospects as periodontal drug delivery systems. Electrospinning technology and electrospinning fibers as periodontal drug delivery systems are reviewed in terms of drug loading methods, drug loading types, modes of action, application forms and prospects.
Electrospinning technology has the advantages of wide sources of raw materials, simple process, small fiber diameter and high porosity. These characteristics make electrospinning technology widely used in biomedicine, energy and catalysis, especially in electrospinning polymers in various aspects of biomedical engineering.
In summary, electrospinning technology has important application value in dentistry and tissue engineering, especially in the preparation of nanofiber scaffolds with specific structures and functions. The research results of Tao Jiang's team demonstrated the potential of electrospinning technology in alveolar bone regeneration and repair after tooth extraction, which provides new possibilities for improving the success rate of dental implants and overall oral health.
Electrospinning Nanofibers Article Source:
https://doi.org/10.1016/j.ijbiomac.2024.129454
